Chimeric flavivirus between Binjari virus and Dengue virus serotype-2
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7kv8
Q-score: 0.701
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Binjari virus (11 MDa, Virus from Binjari virus)
- (2s,3r,4z)-3-hydroxy-2-[(9e)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate (643 Da, Ligand)
- Envelope protein e (54 kDa, Protein from Dengue virus 2)
- M and e from dengue virus serotype-2 isolate et300 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Dengue virus 2)
- Water (18 Da, Ligand)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Matrix protein m (8 kDa, Protein from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Chimeric flavivirus between Binjari virus and West Nile (Kunjin) virus
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7kv9
Q-score: 0.588
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Matrix protein m (8 kDa, Protein from Kunjin virus)
- Binjari virus (11 MDa, Virus from Binjari virus)
- M and e from west nile virus isolate nsw2011 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Kunjin virus)
- Envelope protein e (53 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of West Nile virus (Kunjin)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7kva
Q-score: 0.555
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Kunjin virus (22 MDa, Virus from Kunjin virus)
- Envelope protein e (53 kDa, Protein from Kunjin virus)
- Matrix protein m (8 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Chimeric flavivirus between Binjari virus and Murray Valley encephalitis virus
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7kvb
Q-score: 0.48
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Binjari virus (11 MDa, Virus from Binjari virus)
- Envelope protein e (53 kDa, Protein from Murray Valley encephalitis virus)
- M and e from murray valley encephalitis virus strain mve-1-51 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Murray Valley encephalitis virus)
- Matrix protein m (8 kDa, Protein from Murray Valley encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM reconstruction of the mature chimeric BinJV/ZIKV-prME virion
Hobson-Peters J, Harrison JJ, Watterson D, Hazlewood JE, Vet LJ, Newton ND, Warrilow D, Colmant AMG, Taylor C, Huang B, Piyasena TBH, Chow WK, Setoh YX, Tang B, Nakayama E, Yan K, Amarilla AA, Wheatley S, Moore PR, Finger M, Kurucz N, Modhiran N, Young PR, Khromykh AA, Bielefeldt-Ohmann H, Suhrbier A, Hall RA
Sci Transl Med (2019) 11 [ Pubmed: 31826984 DOI: doi:10.1126/scitranslmed.aax7888 ]
- Zika virus (Virus from Zika virus)
Cryo-EM reconstruction of the mature chimeric BinJV/ZIKV-prME virion in complex with Fab C8
Hobson-Peters J, Harrison JJ, Watterson D, Hazlewood JE, Vet LJ, Newton ND, Warrilow D, Colmant AMG, Taylor C, Huang B, Piyasena TBH, Chow WK, Setoh YX, Tang B, Nakayama E, Yan K, Amarilla AA, Wheatley S, Moore PR, Finger M, Kurucz N, Modhiran N, Young PR, Khromykh AA, Bielefeldt-Ohmann H, Suhrbier A, Hall RA
Sci Transl Med (2019) 11 [ Pubmed: 31826984 DOI: doi:10.1126/scitranslmed.aax7888 ]
- Zika virus (Virus from Zika virus)
Cryo-EM reconstruction of the immature chimeric BinJV/ZIKV-prME virion
Hobson-Peters J, Harrison JJ, Watterson D, Hazlewood JE, Vet LJ, Newton ND, Warrilow D, Colmant AMG, Taylor C, Huang B, Piyasena TBH, Chow WK, Setoh YX, Tang B, Nakayama E, Yan K, Amarilla AA, Wheatley S, Moore PR, Finger M, Kurucz N, Modhiran N, Young PR, Khromykh AA, Bielefeldt-Ohmann H, Suhrbier A, Hall RA
Sci Transl Med (2019) 11 [ Pubmed: 31826984 DOI: doi:10.1126/scitranslmed.aax7888 ]
- Zika virus (Virus from Zika virus)
Muller DA, Landsberg MJ, Bletchly C, Rothnagel R, Waddington L, Hankamer B, Young PR
J Gen Virol (2012) 93 pp. 771-779 [ DOI: doi:10.1099/vir.0.039321-0 Pubmed: 22238236 ]
- Secreted form of denv-2 ns1 (246 kDa, Sample)
- Non structural protein 1 (41 kDa, Protein from Dengue virus 2)